Georg Waeg Selected Research

4-hydroxy-2-nonenal (4-hydroxynonenal)

10/2023	Relationship between 4-Hydroxynonenal (4-HNE) as Systemic Biomarker of Lipid Peroxidation and Metabolomic Profiling of Patients with Prostate Cancer.
1/2022	Post-mortem Findings of Inflammatory Cells and the Association of 4-Hydroxynonenal with Systemic Vascular and Oxidative Stress in Lethal COVID-19.
8/2021	Preliminary Findings on the Association of the Lipid Peroxidation Product 4-Hydroxynonenal with the Lethal Outcome of Aggressive COVID-19.
1/2021	Association of Lipid Peroxidation Product 4-Hydroxynonenal with Post-Traumatic Stress Disorder.
2/2020	The Appearance of 4-Hydroxy-2-Nonenal (HNE) in Squamous Cell Carcinoma of the Oropharynx.
1/2017	4-hydroxynonenal causes impairment of human subcutaneous adipogenesis and induction of adipocyte insulin resistance.
4/2013	The effects of angiotensin II and the oxidative stress mediator 4-hydroxynonenal on human osteoblast-like cell growth: possible relevance to otosclerosis.
2/2013	Stobadine attenuates impairment of an intestinal barrier model caused by 4-hydroxynonenal.
1/2010	Growth suppression of human breast carcinoma stem cells by lipid peroxidation product 4-hydroxy-2-nonenal and hydroxyl radical-modified collagen.
1/2010	Lipid peroxidation product 4-hydroxynonenal as factor of oxidative homeostasis supporting bone regeneration with bioactive glasses.

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Georg Waeg Research Topics

Disease

9	Neoplasms (Cancer) 10/2023 - 01/2005
3	Inflammation (Inflammations) 01/2021 - 04/2007
2	COVID-19 01/2022 - 08/2021
2	Cognitive Dysfunction 01/2021 - 01/2010
2	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2020 - 08/2019
2	Insulin Resistance 01/2017 - 01/2017
2	Atherosclerosis 01/2015 - 04/2003
2	Peptic Ulcer (Peptic Ulcers) 02/2013 - 03/2008
2	Osteosarcoma (Osteogenic Sarcoma) 01/2007 - 08/2006
1	Prostatic Neoplasms (Prostate Cancer) 10/2023
1	Critical Illness (Critically Ill) 08/2021
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2021
1	Skin Diseases (Skin Disease) 10/2020
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 02/2020
1	Carcinogenesis 02/2020
1	Obesity 01/2017
1	Hepatocellular Carcinoma (Hepatoma) 01/2017
1	Liver Neoplasms (Liver Cancer) 01/2017
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2017
1	Lung Neoplasms (Lung Cancer) 10/2016
1	Carcinoma (Carcinomatosis) 10/2016
1	Adenocarcinoma 10/2016
1	Autoimmune Diseases (Autoimmune Disease) 01/2016
1	Conductive Hearing Loss 04/2013
1	Otosclerosis 04/2013
1	Colonic Neoplasms (Colon Cancer) 02/2013
1	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2012
1	Cardiovascular Diseases (Cardiovascular Disease) 05/2012
1	Hyperoxia 02/2010
1	Hepatitis 02/2010
1	Neuroblastoma 01/2010
1	Breast Neoplasms (Breast Cancer) 01/2010
1	Alzheimer Disease (Alzheimer's Disease) 01/2010
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2010
1	Bone Fractures (Bone Fracture) 01/2010
1	Brain Injuries (Brain Injury) 11/2009
1	Body Weight (Weight, Body) 05/2009
1	Atherosclerotic Plaque (Atheroma) 04/2007
1	Astrocytoma (Pilocytic Astrocytoma) 01/2005
1	Coronary Stenosis (Coronary Artery Stenosis) 04/2003
1	Myocardial Infarction 04/2003
1	Coronary Artery Disease (Coronary Atherosclerosis) 04/2003

Drug/Important Bio-Agent (IBA)

13	4-hydroxy-2-nonenal (4-hydroxynonenal)IBA 10/2023 - 01/2007
11	Proteins (Proteins, Gene)FDA Link 08/2021 - 01/2005
5	Biomarkers (Surrogate Marker)IBA 10/2023 - 01/2016
4	AntioxidantsIBA 10/2023 - 02/2010
3	Monoclonal AntibodiesIBA 10/2023 - 01/2005
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 04/2013
3	LipidsIBA 08/2019 - 10/2016
3	AldehydesIBA 01/2017 - 01/2007
2	EndocannabinoidsIBA 08/2019 - 10/2016
2	Insulin (Novolin)FDA Link 01/2017 - 01/2017
2	Free RadicalsIBA 04/2013 - 01/2007
2	Histidine (L-Histidine)FDA Link 03/2008 - 01/2005
2	AlbuminsIBA 04/2007 - 08/2006
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2023
1	Blood Proteins (Serum Proteins)IBA 10/2023
1	Linoleic Acid (Linoleate)IBA 10/2023
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 10/2023
1	Proteasome Endopeptidase Complex (Proteasome)IBA 10/2020
1	Phospholipases (Phospholipase)IBA 08/2019
1	Sorafenib (BAY 43-9006)FDA Link 01/2017
1	Cardiolipins (Cardiolipin)IBA 01/2017
1	Metformin (Glucophage)FDA LinkGeneric 01/2017
1	StaurosporineIBA 01/2017
1	Glutathione (Reduced Glutathione)IBA 10/2016
1	CatalaseIBA 10/2016
1	Glutathione PeroxidaseIBA 10/2016
1	ElastinIBA 01/2015
1	Capsules (Microcapsules)IBA 04/2013
1	Angiotensin IIIBA 04/2013
1	Peptides (Polypeptides)IBA 04/2013
1	Protein Isoforms (Isoforms)IBA 02/2010
1	PPAR gammaIBA 02/2010
1	PPAR-betaIBA 02/2010
1	Oxidants (Oxidizing Agents)IBA 02/2010
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 02/2010
1	Hydroxyl RadicalIBA 01/2010
1	Caspase 3 (Caspase-3)IBA 01/2010
1	CollagenIBA 01/2010
1	Acrolein (Aqualin)IBA 01/2010
1	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 05/2009
1	Receptor for Advanced Glycation End ProductsIBA 04/2007
1	EpitopesIBA 04/2007
1	ParaffinIBA 01/2005
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2005
1	Hematoxylin (Haematoxylon)IBA 01/2005
1	AutoantibodiesIBA 04/2003
1	LDL Lipoproteins (beta Lipoproteins)IBA 04/2003
1	low density lipoprotein inhibitorIBA 04/2003
1	oxidized low density lipoproteinIBA 04/2003

Therapy/Procedure

2	Therapeutics 10/2016 - 01/2010
1	Critical Care (Surgical Intensive Care) 08/2021
1	Drug Therapy (Chemotherapy) 01/2010